Ultrahigh-Molecular-Weight Polyethylene
Weihong Jin, Paul K. Chu, maEncyclopedia of Biomedical Engineering, 2019
UHMWPEhe laina lainapolyolefinme kahi hui hou o − CH2CH2 −.He mau kaulahao lōʻihi ko UHMWPE lāʻau lapaʻau me kamolecular masso 2 × 106–6 × 106 g mol− 1 a he apolimer semirystallineme kahi pūʻulu o nā ʻāpana i hoʻopaʻa ʻia i loko o kahi huikaupae amorphous(Turell a me Bellare, 2004).He haʻahaʻa haʻahaʻa ka UHMWPE, ke kūpaʻa lole kiʻekiʻe, ka paʻakikī maikaʻi, kiʻekiʻeikaika hopena, kū'ē kiʻekiʻe i nā kemika corrosive, biocompatibility maikaʻi loa, a me ke kumu kūʻai haʻahaʻa.
Ua hoʻohana ʻia ʻo UHMWPE i nā lāʻau lapaʻauhui implantsno nā makahiki he 40, ʻoi aku hoʻi ma ke ʻano he liner articular i kahi hoʻololi āpau āpau a me ka hoʻokomo ʻana i ka tibial i nā pani kuli holoʻokoʻa.I ka makahiki 1962, ua hoʻohana mua ʻia ʻo UHMWPE e like me nā ʻāpana acetabular a ua lilo i mea nuimea halihalii nā pani pani āpau mai ka 1970s.Eia naʻe, ʻo ka ʻaʻahu ʻana o UHMWPE e pili ana me nā ʻāpana ʻoi aku ka paʻakikī i hana ʻia me nā metala a i ʻole nā ceramics he pilikia nui i ka orthopedics i nā makahiki 1980 ma muli o ka hoʻomau mau ʻana o nā kaulahao polymer.Hiki ke hoʻoulu ʻia ka ʻōpalaosteolysiske alakaʻi nei i ka wehe ʻana o nā implants a me ka nāwaliwali o ke ʻano iwi.
Loaʻa ka holomua nui i ka hoʻomohala ʻana i ka UHMWPE pili nui i ka hopena o nā makahiki 1990.Hoʻohana nui ʻia ka hoʻopili ʻana i ka UHMWPE ma o ka hoʻokalakala ʻana i nā kaulahao ʻaoʻao me ka radiation e like meray gamma,uila uila, a i ʻole nā mea kemika e like me ka peroxide e hoʻomaikaʻi ai i ke kūpaʻa ʻana ma muli o ka emi ʻana o ka neʻe ʻana o nā kaulahao polymer ma hope o ka hoʻopili ʻana (Lewis, 2001).E hoʻomaikaʻi i kaoxidationke kūʻē ʻana, mālama ʻia ka UHMWPE i hoʻopili ʻia me ka wela.Ua hoʻohana maikaʻi ʻia ka UHMWPE i hoʻopaʻa ʻia i ka ukanaamia lilo i mea maʻamau i nā pani āpau āpau.
Ma mua o ka hoʻokomo ʻia ʻana, hoʻomaʻemaʻe ʻia nā implants orthopedic e ka irradiation gamma i ka ea ambient.Hoʻoulu ka Gamma ray i ka hoʻokumu ʻana o nā radical manuahi ma o ka ʻoki ʻana i ke kaulahao.Ma hope o ka gamma irradiation, hiki i nā radical manuahi ke noho i loko o ka polymer a hana pū me nā ʻano O i loaʻa i ka wā o ka mālama ʻana a i ʻole in vivo induce detrimental oxidation o UHMWPE (Premnath et al., 1996).ʻOiai ua hoʻonui ʻia ka UHMWPE i hoʻopili nui ʻia i ka lole, nā waiwai ʻē aʻe e like me ka ductility,ʻoʻoleʻa haʻihaʻi, pale luhi, aikaika tensilehiki ke hoʻopili ʻia e ka gamma irradiation (Lewis, 2001; Premnath et al., 1996).
ʻO nā ʻano nonionizing e like me ka sterilization me ka hoʻohana ʻana i ka ethylene oxide gas a i ʻolekinoea plasmapuka mai, a ua mālama ʻia kekahi mālama hoʻomaha ma hope o ka hoʻopili ʻana e hoʻopau i ka hopena deleterious i ʻōlelo ʻia ma mua (Kurtz et al., 1999).ʻO ka antioxidantvitamina Eua hoʻokomo pū ʻia i loko o ka UHMWPE i hoʻopaʻa ʻia e hoʻopaʻa i ka oxidation ma ka pane ʻana me nā radical manuahi (Bracco and Oral, 2011).
ʻAʻohe mau moʻolelo lapaʻau i nā mea hoʻololi hui ʻoiai ke hōʻike nei ka huaora E i ka palekana a me ka biocompatibility.No laila, makemake ʻia nā ʻano e hoʻoikaika ai i ke kūpaʻa ʻaʻahu me ka ʻole o ka hōʻino ʻana i nā mea pono ʻē aʻe o ka UHMWPE a me ka noi lapaʻau lōʻihi no UHMWPE manā noi orthopedic.
Ka manawa hoʻouna: Iune-26-2023
