Ultrahigh-Molecular-Weight Polyethylene
Weihong Jin, Paul K. Chu, mukatiEncyclopedia yeBiomedical Engineering, 2019
UHMWPEane mutsarapolyolefinine yuniti inodzokorora ye - CH2CH2 -.Medical-giredhi UHMWPE ine cheni refu ine amolecular massye2 × 106–6 × 106 g mol− 1 uye isemicrystalline polymerine seti yematunhu akarongedzerwa akaiswa mune isina kurongekaamorphous phase(Turell naBellare, 2004).UHMWPE ine yakaderera friction, yakakwirira kupfeka kuramba, kunaka kusimba, yakakwirirasimba rekuita, kupikisa kwakanyanya kumakemikari anoparadza, biocompatibility yakanakisa, uye mutengo wakaderera.
UHMWPE yakashandiswa kukiriniki mukatijoint kudyarakweanopfuura makore makumi mana, kunyanya searticular liner mune yakazara hudyu inotsiviwa uye tibial inoisa mune yakazara mabvi ekutsiva.Muna 1962, UHMWPE yakatanga kushandiswa seacetabular components uye yave iyo inotonga.kutakura zvinhumukutsiviwa kwehudyu kubva kuma1970s.Zvakadaro, kupfekwa kweUHMWPE mukusangana nezvinhu zvakaomarara zvakagadzirwa nesimbi kana simbi raive dambudziko guru mukurapa kwemapfupa muma1980s zvakanyanya nekuda kwekuenderera mberi kwekugadzirisazve cheni dzepolymer.Mamiriro ekunze anogona kukonzeraosteolysiszvichiita kuti kusunungurwa kwezvipimo uye kupera simba kwehutano hwemapfupa.
Pakave nebudiriro huru mukuvandudzwa kweiyo yakanyanya-yakabatana UHMWPE mukupera kwema1990.Cross-linking yeUHMWPE inoshandiswa zvakanyanya nekuita radicalizing macheni epadivi nemwaranzi sengegamma ray,electron danda, kana makemikari akadai seperoxide kuti avandudze kusakara nekuda kwekuderera kwekufamba kwemaketani epolymer mushure mekubatanidza (Lewis, 2001).Kuvandudzaoxidationkuramba, iyo muchinjiko-yakabatana UHMWPE inorapwa nemafuta.Yakanyanya kuyambuka-yakabatana UHMWPE yakashandiswa zvinobudirira mukutakurisa-kutakuramajoiniuye inova chiyero mukutsiviwa kwehudyu yose.
Asati adyarwa, ma implants emapfupa anowanzo itwa sterilized ne gamma irradiation mumhepo iri mumhepo.Gamma ray inokonzera kuumbwa kwemahara radicals kuburikidza neketani cleavage.Mushure me gamma irradiation, mahara radicals anogona kunge achiripo mupolymer uye anoita neanowanikwa O marudzi panguva yekuchengetera kana mu vivo anokonzera kukanganisa oxidation yeUHMWPE (Premnath et al., 1996).Kunyangwe yakanyanya kuyambuka-yakabatana UHMWPE yakawedzera kupfeka kuramba, zvimwe zvivakwa zvakaita se ductility,kutyoka kuoma, kuramba kuneta, uyetensile simbainogona kukanganiswa ne gamma irradiation (Lewis, 2001; Premnath et al., 1996).
Nonionizing nzira dzakadai sekuita sterilization uchishandisa ethylene oxide gasi kanagasi plasmakubuda, uye kumwe kurapa kwekudzikamisa kwakaitwa zvakare mushure mekubatanidza-kubatanidza kubvisa pesvedzero yakaipa yambotaurwa (Kurtz et al., 1999).Iyo antioxidantvitamini Einosanganisirwa muchinjika-yakabatana UHMWPE kudzvanya oxidation nekuita nemahara radicals (Bracco uye Oral, 2011).
Hapasati pasisina nhoroondo yekiriniki mumajoini ekutsiva zvikamu kunyangwe vhitamini E ichiratidza kuchengeteka uye biocompatibility.Naizvozvo, nzira dzekusimudzira kuramba kupfeka pasina kukanganisa chero zvimwe zvakakosha zveUHMWPE uye yenguva refu yekiriniki application inodiwa kune UHMWPE mu.maitiro emapfupa.
Nguva yekutumira: Jun-26-2023
