Ultrahigh-Molecular-Weight Polyethylene
Weihong Jin, Paul K. Chu, inEncyclopedia of Biomedical Engineering, 2019
UHMWPEbụ linearpolyolefinna nkeji ugboro ugboro - CH2CH2 -.UHMWPE ọkwa ahụike nwere agbụ ogologo nwere amolekul ukanke 2 × 106–6 × 106 g mol-1 ma bụrụ apolymer nke semirystallineya na mpaghara ndị enyere iwu agbakwunyere n'ime ọgba agharaamorphous agba(Turell na Bellare, 2004).UHMWPE nwere esemokwu dị ala, nkwụsi ike dị elu, ịdị mma dị mma, dị elummetụta ike, nnukwu iguzogide kemịkalụ na-emebi emebi, ezigbo biocompatibility, yana ọnụ ala dị ala.
Ejirila UHMWPE n'ụlọ ọgwụnkwonkwo etinyereruo ihe karịrị afọ 40, karịsịa dị ka ihe ọkpụkpụ articular na ngụkọta ngbanwe hip na ntinye tibial na ngụkọta ikpere.Na 1962, UHMWPE bu ụzọ jiri dị ka akụrụngwa acetabular wee bụrụ nke kachasịebu ihena ngụkọta ndochi hip kemgbe 1970s.Agbanyeghị, iyi UHMWPE na kọntaktị na ihe ndị siri ike nke ọla ma ọ bụ ceramik mere bụ nnukwu nsogbu na orthopedics na 1980s tumadi n'ihi nhazigharị nke ụdọ polymer na-aga n'ihu.Ihe mkpuchi mkpuchi nwere ike ịkpataosteolysisna-eduga n'ịtọpụ ihe ndị a na-etinye n'ime ya na adịghị ike nke nhazi ọkpụkpụ.
Enwere nnukwu ọganihu na mmepe nke UHMWPE nwere njikọ chiri anya na ngwụcha 1990s.A na-emejuputa njikọ njikọ nke UHMWPE n'ọtụtụ ebe site na iji radieshon mee ka ụzarị dị n'akụkụ dị kagamma ray,eletrọn ọkụ, ma ọ bụ kemịkalụ dị ka peroxide iji melite nguzogide eyi n'ihi mbelata ngagharị nke ụdọ polymer mgbe njikọ gafere (Lewis, 2001).Iji meliteoxidationNguzogide, UHMWPE ejikọtara obe na-agwọ ya nke ọma.Ejila UHMWPE nwere njikọ gafere nke ọma na ibu ibunkwonkwona-aghọ ọkọlọtọ na ngụkọta hip nnọchi.
Tupu etinyere ya, a na-ekpochapụ ihe ndị na-etinye orthopedic site na irradiation gamma na ikuku gburugburu.Gamma ray na-akpalite nguzobe nke free radicals site na mgbawa agbụ.Mgbe irradiation gamma gasịrị, radicals free nwere ike ịdị na polymer wee meghachi omume na ụdị O dị n'oge nchekwa ma ọ bụ na vivo na-ebute oxidation nke UHMWPE (Premnath et al., 1996).Agbanyeghi na UHMWPE nwere njikọ chiri anya emeela ka nguzogide iyi, ihe ndị ọzọ dị ka ductility,mgbaji siri ike, ike ọgwụgwụ, naike ọdụdọgamma irradiation nwere ike imebi (Lewis, 2001; Premnath et al., 1996).
Ụzọ ndị na-adịghị eme ihe dị ka igba ogwu na-eji ethylene oxide gas ma ọ bụgas plasmapụta, na ụfọdụ ọgwụgwọ nkwụsi ike emewokwa ka emechara njikọ njikọ iji kpochapụ mmetụta ọjọọ nke a kpọtụrụ aha na mbụ (Kurtz et al., 1999).Ihe antioxidantvitamin Eetinyekwara ya n'ime UHMWPE ejikọtara ọnụ iji kwụsị oxidation site na imeghachi omume na radicals efu (Bracco na Oral, 2011).
Enweghị akụkọ ihe mere eme nke ụlọ ọgwụ na nkwonkwo ngbanwe n'agbanyeghị na vitamin E na-egosipụta nchekwa na biocompatibility.Ya mere, ụzọ iji kwalite nguzogide iyi na-emebighị ihe ndị ọzọ dị mkpa nke UHMWPE na ngwa ụlọ ọgwụ ogologo oge ka achọrọ maka UHMWPE nangwa orthopedic.
Oge nzipu: Jun-26-2023
