Taw qhia rau hip cog thiab kuaj biomarker
Ilona Świątkowska, ... Alister J. Hart, hauvBiomarkers ntawm Hip Implant FunctionIb., 2023
1.2.1.2 Yas Polymers
Ultra-high-molecular-yuagpolyethylene(UHMWPE) is asemicrystalline polymernrog rau keeb kwm ntev ntawm kev siv hauvorthopedicapps, tshwj xeeb tshaj yog nyob rau hauvacetabularliners rauTHR cog.Cov khoom siv tsis tshua muaj coefficient ntawm kev sib txhuam, yog biocompatible, thiab pheej yig los tsim.
Txawm li cas los xij, thaum nyob rau hauv kev sib cuag nrog cov tawv tawv, UHMWPE tso tawm micrometer-qhov loj me, uas tuaj yeem ua raupob txha resorptionnyob ib ncig ntawmcog(periprosthetic osteolysis),aseptic loosening(poob ntawm implant fixation thaum tsis muaj kab mob), thiab thaum ntxov mechanical tsis ua hauj lwm.Txhawm rau txo qhov tshwm sim ntawm qhov tsis zoo no, kev siv zog ntau tau ua kom nce qib ntawm kev sib txuas hauv UHMWPE.
Thawj-tiam heev crosslinked UHMWPE (HXLPE) liners, clinically qhia nyob rau hauv lub 1990s, tau gamma irradiated thiab ces thermally ua tiav (annealed los yog remelted) los txhim kho lawv cov tsis kam musdawb radicalstsim thaum lub sij hawm irradiation.Cov txheej txheem tsis tau ua tiav cov txiaj ntsig zoo: annealing ua tsis tiav los tshem tawm tag nrho cov dawb radicals, thaum remelting ua rau cov khoom siv uas tsis tuaj yeem kuaj dawb radicals tab sis txo qis.crystallinitythiab ua rau muaj kev cuam tshuam rau kev qaug zog tawg (Kurtz li al., 2011).
Txhawm rau sim daws cov teeb meem no, tiam tom ntej ntawm HXLPE liners tsom kom ua tiav oxidative tsis kam thaum tuav lub siab hnav tsis kam ntawm cov khoom siv thawj zaug thiab cov khoom siv kho tshuab.zogntawm pa polyethylene;Ob txoj hauv kev siv tau ua ntu zus irradiation thiab annealing, thiabvitamin Edoping (vitamin E ua raws li cov dawb radical scavenger) (D'Antonio li al., 2012; Oral and Muratoglu, 2011).
Txawm hais tias muaj kev txhawj xeeb thawj zaug, thawj tiam HXLPE ua rau pom cov duab hluav taws xob zoo heev thiab ua haujlwm ntev, txawm tias cov hluas thiab nquag.cov neeg mob(Lim et al., 2019).Thib ob tiam HXLPE xa cov txiaj ntsig luv luv mus rau nruab nrab lub sijhawm, tab sis kev soj ntsuam mus sij hawm ntev yuav tsum tau ua kom paub tseeb tias cov qauv no puas muaj txiaj ntsig zoo dua li cov thawj tiam (Langlois thiab Hamadouche, 2020).
Post lub sij hawm: Jun-26-2023
