Intshayelelo yokufakelwa kwe-hip kunye novavanyo lwe-biomarker
Ilona Świątkowska, ... Alister J. Hart, inIi-Biomarkers ze-Hip Implant Function, 2023
1.2.1.2 Iipholima zeplastiki
I-Ultra-high-molecular-weighti-polyethylene(UHMWPE) yii-semicrystalline polymerngembali ende yokusetyenziswa kwiugqirha wamathamboizicelo, ngakumbi kwii-acetabulariilayini zeTHR ukufakelwa.Izinto eziphathekayo zine-coefficient ephantsi ye-friction, i-biocompatible, kwaye ayibizi ukuvelisa.
Nangona kunjalo, xa udibana nemigangatho eqinile, i-UHMWPE ikhupha amasuntswana angama-micrometer, anokukhokelelaukubuyisela amathambongeenxa zonke kwiukufakelwa(i-periprosthetic osteolysis),ukukhululwa kwe-aseptic(ukulahleka kokulungiswa kokufakelwa ngokungabikho kosulelo), kunye nokusilela kwangethuba komatshini.Ukunciphisa ukuxhaphaka kwezi ziphumo zibi, umzamo omkhulu owenziweyo wokwandisa iqondo lokuwela phakathi kwe-UHMWPE.
Isizukulwana sokuqala se-UHMWPE (HXLPE) iilayini eziqhagamshelwe kakhulu, zaziswa ngokweklinikhi kwiminyaka yoo-1990, zafakwa i-gamma irradiated kwaye emva koko zacutshungulwa ngokushushu (zifakwe okanye zinyibilikisiwe) ukuphucula ukuxhathisa kwazo.free radicalsyenziwe ngexesha lokukhanya.Akukho nkqubo ivelise iziphumo ezigqibeleleyo: ukudibanisa kusilele ukuphelisa zonke iiradicals zasimahla, ngelixa ukunyibilika kukhokelela kwisixhobo esingenakubonwa ngeeradicals zasimahla kodwa zincitshisiwe.ubukhazikhazikunye nokwanda kokuchaphazeleka kokuphazamiseka kokukhathala (Kurtz et al., 2011).
Ukuzama ukujongana nale miqobo, isizukulwana esilandelayo se-HXLPE liners sijolise ekufezekiseni ukuchasana kwe-oxidative ngelixa sigcina ukuxhatshazwa okuphezulu kwempahla yesizukulwana sokuqala kunye noomatshini.amandlai-polyethylene eqhelekileyo;iindlela ezimbini ezisetyenzisiweyo yayiyi-irradiation elandelelanayo kunye nokunciphisa, kunyeivithamin Ei-doping (i-vitamin E isebenza njenge-scavenger yamahhala) (D'Antonio et al., 2012; Oral and Muratoglu, 2011).
Ngaphandle kweenkxalabo zokuqala, isizukulwana sokuqala i-HXLPE sibonisa iziphumo ezigqwesileyo zeradiographic kunye nokuphila ixesha elide, nokuba kuncinci kwaye kusebenza.izigulane(Lim et al., 2019).Isizukulwana sesibini i-HXLPE yazisa iziphumo ezithembisayo ezimfutshane ukuya phakathi kwexesha elide, kodwa ukulandelwa kwexesha elide kuya kufuneka ukuba kuqinisekiswe ukuba ngaba olu yilo lunenzuzo yeklinikhi ngaphezu kwee-liners zesizukulwana sokuqala (uLanglois noHamadouche, ngo-2020).
Ixesha lokuposa: Jun-26-2023
