Isingeniso sokufakwa kwe-hip kanye nokuhlolwa kwe-biomarker
Ilona Świątkowska, ... Alister J. Hart, inAma-Biomarker we-Hip Implant Function, 2023
1.2.1.2 Amapholima epulasitiki
Isisindo samangqamuzana aphezulu kakhului-polyethylene(UHMWPE) ii-semicrystalline polymerenomlando omude wokusetshenziswa kuudokotela wamathamboizicelo, ikakhulukazi kui-acetabularliners forI-THR izimila.Impahla ine-coefficient ephansi yokungqubuzana, i-biocompatible, futhi akubizi ukuyikhiqiza.
Kodwa-ke, lapho ithintana nezindawo eziqinile, i-UHMWPE ikhipha izinhlayiya ezinosayizi omncane wemitha, ezingaholela ekutheniithambo resorptionnxazonke kwegxilisa(i-periprosthetic osteolysis),ukususwa kwe-aseptic(ukulahlekelwa ukulungiswa kokufakelwa lapho kungekho ukutheleleka), kanye nokwehluleka kwemishini ekuqaleni.Ukunciphisa ukusabalala kwale miphumela emibi, mkhulu umzamo owenziwe ukuze kwandiswe izinga lokuxhumanisa phakathi kwe-UHMWPE.
Amalayini esizukulwane sokuqala e-UHMWPE (HXLPE) axhumene kakhulu, awethulwa ngokomtholampilo ngeminyaka yawo-1990s, afakwa imisebe ye-gamma futhi acutshungulwa ngokushisa (afakwe noma ancibilika) ukuze kuthuthukiswe ukumelana kwawo.ama-radicals mahhalaidalwe ngesikhathi sokushiswa kwemisebe.Ayikho inqubo eyaveza imiphumela ephelele: ukukhishwa kwehlulekile ukuqeda wonke ama-radicals mahhala, kuyilapho ukuncibilika kubangele into enama-radicals mahhala angabonakali kodwa ancishisiwe.ubucwebekanye nokwanda kokungenwa kokukhathala kokuqhekeka (Kurtz et al., 2011).
Ukuzama ukubhekana nalezi zihibe, isizukulwane esilandelayo se-HXLPE liners sihlose ukuzuza ukumelana ne-oxidative ngenkathi silondoloza ukumelana okuphezulu kokugqokwa kwezinto zesizukulwane sokuqala kanye nomshini.amandlai-polyethylene evamile;izindlela ezimbili ezisetshenzisiwe kwakuyi-radiation elandelanayo kanye ne-annealing, kanyevitamin Ei-doping (uvithamini E usebenza njenge-scavenger yamahhala) (D'Antonio et al., 2012; Oral and Muratoglu, 2011).
Naphezu kokukhathazeka kokuqala, i-HXLPE yesizukulwane sokuqala ibonisa imiphumela emihle kakhulu ye-radiographic nokuphila isikhathi eside, ngisho nasebancane nabasebenzayo.iziguli(Lim et al., 2019).I-HXLPE yesizukulwane sesibili ilethe imiphumela ethembisayo yesikhathi esifushane ukuya maphakathi, kodwa kuzodingeka ukulandelelwa kwesikhathi eside ukuze kuqinisekiswe ukuthi le miklamo inenzuzo yomtholampilo ngaphezu kwamalayini esizukulwane sokuqala (uLanglois noHamadouche, 2020).
Isikhathi sokuthumela: Jun-26-2023
